Methotrexate, How And When To Use It

Methotrexate is commonly used to treat rheumatoid arthritis as well as other rheumatic conditions. This drug is classified as a Disease-Modifying Anti-Rheumatic Drug or DMARD because it helps to reduce pain as well as the swelling associated with arthritis. It can also help to lessen joint damage thereby lowering the risk of long-term disability. You have to be on this drug for at least six weeks to see some improvement in your condition. Normally it takes 12 weeks or even 6 months for full results to be realized.

This drug had been used to treat psoriasis and cancer before its approval for rheumatoid arthritis. It is also used to treat other rheumatic conditions such as lupus, anklosing spondylitis, vasculitis and juvenile arthritis. Methotrexate has several side effects. It is said to block dihydrofolate reductase, an enzyme that plays a role in the production of folic acid which crucial for actively growing cells.

This drug can interfere with the normal functioning of the liver. When on this medication, it is important to have blood tests after every 8 to 12 weeks. The blood is drawn from the liver panels and is monitored for side effects. You are not supposed to drink when on this medication because it can cause significant liver damage. Your doctor will give you directions and may permit no more than two drinks a month.

Other possible side effects of methotrexate are nausea, vomiting, mouth sores, rash and diarrhea. Blood count abnormalities, cirrhosis of the liver although rare and persistent cough are other possible side effects. It can also lead to gradual hair loss and sun sensitivity.

Mercy Maranga Reports on Health and Fitness issues. Visit Her Site here for more information on arthritis and its treatmentArthritis